Oshas small business guide for ethylene oxide osha 3359 2009 english. Safety data sheet ethylene oxide linde hiq linde gas. Substance safety data sheet for ethylene oxide nonmandatory. Ethylene oxide sterilization process pdf commercial ethylene oxide sterilization and fumigation operations 40. Oshaniosh spirometry infosheet a spirometry breathing test shows how well you can move air in and out of your lungs. A number of industries use ethylene oxide as a sterilant for heat or moisturesensitive materials or as a fumigant to control microorganisms or insects. Methyloxirane, 12 epoxypropane, methyl ethylene oxide, propylene epoxide. Ethylene oxide is a flammable gas with a somewhat sweet odor. Enter synonyms, trade names or additional information found in section 1. Ethylene oxide, which is considered an air toxic or hazardous pollutant, is released during these operations. Pharmacopoeia eu pharmacopoeia reagents ph eur ref num. Safety data sheet mono ethylene glycol 1 identification of the substancepreparation and companyundertaking application automotive industry. Shortterm exposures can also affect the central nervous system, leading to symptoms such as drowsiness, disorientation, nausea, and vomiting.
Ethylene oxide sds ref al069 air liquide australia limited level 9 380 st. Eogas and anprolene ethylene oxide safety data sheet. The chemical compound 1, 2dichloroethane dce commonly known by its old name of ethylene. It is not intended to serve as a substitute for indepth training or.
Ethylene oxide is also used as a sterilizing agent for medical equipment and a fumigating agent for spices. The reaction is exothermic and eo is recovered from the gas stream, purified and stored. Our msds database is an easy to use, do it yourself tool, and best of all. Cgapg05 use a back flow preventive device in the piping.
National institute for occupational safety and health niosh current intelligence bulletin 35, may 22. Commissioning demonstrates that the sterilization equipment intended for. Pdf production of ethylene and its commercial importance. Dec 06, 2015 related with material safety data sheet. The odor of pure ethylene oxide is not detectable by many people below about 700 ppm, and while impurities present in the industrial material reduce the odor threshold considerably, odor is not a reliable guide to its presence, and artificial means are necessary. Studyhazard statement category 1 category 2 category 3 category 4 category 5. Validation is the total process starting with commissioning, followed by performance qualification. Oshaniosh spirometry infosheet a spirometry breathing test shows how well you can move air.
Safety data sheet ethylene glycol deep south chemical, inc. Ethylene oxide biodegradation rate constants measured at a fullscale wastewater treatment plant were 0. Eto is used in the manufacture of ethylene glycol, surfactants, ethanolamines, glycol ethers, and other organic. Because ethylene oxide is a gas, most is expected to be released to the air where it reacts with water vapor and sunlight and breaks down within a few days. Although ethylene oxide is a hazardous material in terms of flammability, reactivity and toxicity, it can be distributed and handled safely provided that appropriate precautions are observed. July 1, 2014 product uses1,4 ethylene is primarily used as a reactive monomer chemical building block make polyethylene and as an intermediate in the production of other organic compounds, such as ethylene dichloride and ethylene oxide. Material safety data sheets msdss for the products in your work area. Praxair cannot assure the integrity or accuracy of any version of this document. Volatilization of propylene oxide from the aquatic environment may be an important transport mechanism. Provides a summary source of information of all potential and most. If patient is unconscious, or in case of danger of blackout, transport patient in a stabilised. Dihydrooxirine, dimethylene oxide, ethene oxide, epoxyethane, oxane.
Cpachem is a world leader in custommade multielement calibration standards in inorganic and organic. Ethylene oxide c2h4o safety data sheet sds p4798 praxair, inc. New jersey department of health and senior services, hazardous substance fact sheet, revised november 2009. Ethylene oxide eto fact sheet hazard evaluation system and information service. Epa has concluded that ethylene oxide is carcinogenic to humans by the inhalation route of exposure. Ethylene oxide anpro 3,260 view health effects of ethylene oxide american 1,379 view handling and transportation guide for ethylene. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. This site is like a library, you could find million book here by using search box in the header.
If released to the atmosphere, propylene oxide will react in the vapor phase with photochemically produced hydroxyl radicals with an estimated halflife of approximately 30 days. Ethylene oxide is a manmade chemical that is used primarily to make ethylene glycol a chemical used to make antifreeze and polyester. Ethylene oxide msds pdf ethylene flammability scribd. Ethylene oxide safety data sheet p4798 this sds conforms to u. All books are in clear copy here, and all files are secure so dont worry about it. Hightechnology, highexperienced staff, highquality, highspeed. May 1, 2014 the dow chemical company page 4 of 7 secondary infections, which can lead to pneumonia. It is used to make other chemicals, in welding and as a refrigerant. Safety data sheet air liquide msds document library.
Epa has concluded that ethylene oxide is carcinogenic to humans by the inhalation. Dichlorided4, dichloro1, 2ethaned4, 1, eclipse stephenie meyer free download pdf 2ethylene dichlorided4, ethylene. Ethylene is a natural product produced by many plants. Post no smokingno open flames signs in storage and use areas. As a part of the chemical industrys responsible management of its products, the ethylene oxide panel ethylene oxide safety task group stg, a group comprised of producers and industrial users, developed the ethylene oxide product stewardship manual 3rd edition. Osha publications ethylene oxide occupational safety.
Apf 50 any airpurifying, fullfacepiece respirator gas mask with a chinstyle, front or backmounted canister providing protection against ethylene oxide. Since ethylene oxide hydrolyzes to ethylene glycol which is readily biodegraded, the importance of biodegradation of ethylene oxide in aquatic environments is not able to be accurately assessed2. High purity ethylene oxide hpeo is a colourless, highly reactive and flammable gas at room temperature. The ethylene oxide units are equipped with advanced process control, gas detection and emergency shutdown systems. A simulation model of a reactor for ethylene oxide production. Because of the potential for violent decomposition, containers of ethylene oxide must be properly blanketed with an inert gas and given extraordinary protection against fire exposure store only where temperature will not exceed 125f 52c. Ethylene oxide sterilizers are eligible to operate in florida under the terms of an air general permit agp. Explain the circumstances that make the collection of information necessary. Ril msds ethylene oxide reliance industries limited. Details of the supplier of the safety data sheet 1. The main sources of information for this fact sheet are, for cancer, the.
First group represents mgo or caobased mixed met al oxides and rare earth metal oxides. It is intended to provide general information to persons who may handle or store ethylene oxide. In 1941 modo started to produce ethylene oxide for further production of ethylene glycol. In the early 1960th the production of ethylene oxide based from ethanol and chlorohydrin was not considered cost effective. Styrene oxide is an epoxide that is oxirane in which one of the hydrogens has been replaced by a phenyl group. It is very water soluble and solutions of as little as 4% in water are flammable. Validation of an ethylene oxide sterilization cycle demonstration of the effectiveness of an ethylene oxide sterilization cycle is achieved through the validation process. Health science park 3154 caroline drive haw river, nc 27258 usa information telephone number. Station road, coleshill b46 1jy birmingham united kingdom 01675462424 en english sds ref sds056clp 111 danger. Msds centre is an application for viewing and downloading our product material safety data sheets. Exposure to ethylene oxide may cause headache, nausea, vomiting, diarrhea, breathing difficulty, drowsiness, weakness, exhaustion, eye and skin burns, frostbite, and reproductive effects. The acute shortterm effects of ethylene oxide in humans consist mainly of central nervous. The first study was conducted in male mice exposed by inhalation for up to 12 weeks and lung dna samples were analyzed for levels of 3kras codon 12 mutations. Ethylene oxide solution r2 shelf life on ship date.
The principal application of ethylene oxide is the manufacture of ethene glycol or ethylene glycol and higher alcohols used in automotive antifreeze, explosives, cellophane, synthetic rubbers and lubricants as well as solvents and hydraulic fluids. Download vha dir 77, safe use of ethylene oxide book pdf free download link or read online here in pdf. Ethylene oxide in air can be determined by packed column gas chromatography gc. Testing may be performed on workers who perform jobs that may cause exposure to possible lung hazards, are physically demanding, or. Material safety data sheet ethylene dichloride msds name. Acgih classifies ethylene oxide as a2 suspected human carcinogen. Ethylene oxide is generally synthesized by chlorohydrine process and direct oxidation of ethylene with air, catalyzed by silverag. The ethylene oxide product stewardship guidance manual was prepared by the american chemistry councils ethylene oxideethylene glycols panel panel. Understanding oshas exposure monitoring requirements osha 3325 2007 english. In 1963 modo started a production of ethylene oxide based on direct oxidation from ethylene in stenungsund, sweden. Two new mechanistic studies provided confirmation of the mode of action of ethylene oxide. Iarc classifies ethylene oxide in group 1 carcinogenic to humans. Block copolymer of ethylene oxide and propylene oxide chemical name.
This chemical is on the special health hazard substance list. The following references aid in recognizing and evaluating ethylene oxide hazards in the workplace. It is produced by direct oxidation of ethylene with air or oxygen. Gas to sterilize in a 3m sterivactm ethylene oxide sterilizer. Ethylene oxide is a versatile compound used in the production of other chemicals for a variety of industrial applications and everyday consumer products, including household cleaners, personal care items and fabrics and textiles. The major use of ethylene oxide is as a chemical intermediate in the manufacture of ethylene glycol. Ensure activity of vitally important functions until the arrival of the doctor artificial respiration, inhalation of oxygen, heart massage. Ethylene oxide sterilization process pdf x4e6z9gr7gn3. Ethylene glycol is a meaningful target obtained from cellulose, as about 20 million tons of ethylene glycol is produced annually from ethylene via ethylene oxide in the petrochemical industry. Download ethylene oxide epa book pdf free download link or read online here in pdf. Ethylene oxide eto cas 75218 physical hazards ethylene oxide eto is an extremely flammable and reactive material which is a gas at room temperature. Gestion, experiencia, desarrollo, productividad y confiabilidad. This document is only controlled while on the praxair, inc.
A small amount less than 1% is used to control insects in some stored agricultural products and a very small amount is used in hospitals to sterilize medical. Ethylene oxide rapidly breaks down when released to the environment. Praxair cannot assure the integrity or accuracy of any version of this document after it has been downloaded or removed from our website. Ethylene oxide in presence of water can hydrolyze to ethylene glycol and form poly ethylene oxide which then eventually gets oxidized by air and leads to hotspots that can trigger explosive decomposition. Ethylene dichloride ethylene dichloride ethylene dichloride hazard class. Ethylene oxide will dissolve in water, but most of it will quickly evaporate to the air. Ethylene glycol is mainly used as antifreeze and a precursor to polyethylene terephthalate, and the minor derivatives are glyoxal for crosslinkers, dioxolane for a comonomer of polyacetals and solvent. Supporting statement for the informationcollection requirements of the ethylene oxide eto standard 29 cfr 1910.
Read online ethylene oxide epa book pdf free download link book now. The ethylene oxide product stewardship guidance manual was prepared by the american chemistry councils ethylene oxide ethylene glycols panel panel. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. An estimated bcf of 3 was calculated in fish for ethylene oxide src, using a log kow of 0. Application ethylene oxide can be used as a precursor to synthesize. Ethylene oxide is toxic and has a longterm maximum exposure limit of 5 ppm. Because it reacts readily with other chemicals, hpeo is one of the most versatile intermediates and is used to produce many derivative products.
In order to promote public education and public safety, equal justice for all, a better informed citizenry, the rule of law, world trade and world peace, this legal document is hereby made available on a noncommercial basis, as it is the right of all humans to. Chemical product and company identification product name. Fires caused by ethylene oxide are extinguished by traditional media, including foam, carbon dioxide or water. Copying andor downloading of this information for the purpose of properly. Workers may be harmed from exposure to ethylene oxide. Osha, cma, ansi and canadian whmis standards part i what is the material and what do i need to know in an emergency. This page offers you a single central search interface to find material safety data sheets in our large database. Ethylene oxide is on the right to know hazardous substance list because it is cited by osha, acgih, dot, niosh, ntp, dep, iarc, nfpa and epa. Ethylene oxide is carcinogenic to humans iarc group 1 47 s, seda36, 341. You must narrow down the search by first selecting a country language. Ethylene oxide is produced by a gas phase reaction of ethylene and oxygen over a fixed bed silverbased catalyst in multitubular reactors. Read online vha dir 77, safe use of ethylene oxide book pdf free download link book now. Vha dir 77, safe use of ethylene oxide pdf book manual. It is also an important intermediate in the the manufacture of certain detergents.
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